Compound Detail
CHEMBL6022437
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Basic Information
| ChEMBL ID | CHEMBL6022437 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LLGXFJJDHQGQFX-UHFFFAOYSA-N |
2
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
355.4
MW (Da)
3.31
ALogP
4
HBA
2
HBD
54.0
PSA (Ų)
0.82
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 6 meas. best 6.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.17 | 6.17 | 680.0 | 1 |
| Lysine-specific histone demethylase 1A CHEMBL6136 | IC50 | 6.17 | 6.17 | 680.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 680.0 | nM | 6.17 | Inhibitory Activity Assay: A test compound dissolved in DMSO was added by to a r... | - |
| Lysine-specific histone demethylase 1A | IC50 | = | 680.0 | nM | 6.17 | LSD1 Inhibitory Activity: A test compound dissolved in DMSO was added by to a re... | - |
| Lysine-specific histone demethylase 1A | IC50 | = | 680.0 | nM | 6.17 | LSD1 Inhibitory Assay: A test compound dissolved in DMSO was added by to a react... | - |
| Lysine-specific histone demethylase 1A | IC50 | = | 680.0 | nM | 6.17 | Inhibition Assay: A test compound dissolved in DMSO was added by to a reaction s... | - |
| Lysine-specific histone demethylase 1A | IC50 | = | 680.0 | nM | 6.17 | Inhibition Activity Assay: LSD1: A test compound dissolved in DMSO was added by ... | - |
| Lysine-specific histone demethylase 1A | IC50 | = | 680.0 | nM | 6.17 | Inhibitory Activity Assay: LSD1: A test compound dissolved in DMSO was added by ... | - |
Data from ChEMBL 36 via Core Engine