Compound Detail
CHEMBL6022893
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Basic Information
| ChEMBL ID | CHEMBL6022893 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BSUBWSIKDNCXPO-NTUHNPAUSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
322.3
MW (Da)
1.76
ALogP
5
HBA
2
HBD
110.6
PSA (Ų)
0.71
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| TGF-beta receptor type-1 CHEMBL4439 | IC50 | 7.47 | 6.84 | 34.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| TGF-beta receptor type-1 | IC50 | = | 34.0 | nM | 7.47 | Enzyme Activity Inhibition: 1. Preparation of a 1× kinase buffer: 40 mM Tris (pH... | - |
| TGF-beta receptor type-1 | IC50 | = | 616.0 | nM | 6.21 | Enzyme Activity Inhibition: 1. Preparation of a 1× kinase buffer: 40 mM Tris (pH... | - |
Data from ChEMBL 36 via Core Engine