Compound Detail
CHEMBL6029680
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Basic Information
| ChEMBL ID | CHEMBL6029680 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WOPBYAZGDCKRNR-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
382.5
MW (Da)
3.33
ALogP
6
HBA
1
HBD
67.3
PSA (Ų)
0.75
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 8.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | EC50 | 8.16 | 8.16 | 6.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | EC50 | 7.92 | 7.92 | 12.0 | 1 |
| Proto-oncogene Wnt-1 CHEMBL1255129 | EC50 | 5.59 | 5.59 | 2544.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | EC50 | = | 6.9 | nM | 8.16 | The screening assay for DYRK1A kinase activity: Each compound was dissolved in D... | - |
| Glycogen synthase kinase-3 beta | EC50 | = | 12.0 | nM | 7.92 | The screening assay for GSK3beta kinase activity: Each compound is dissolved in ... | - |
| Proto-oncogene Wnt-1 | EC50 | = | 2544.0 | nM | 5.59 | The screening assay for Wnt activity: SW480 colon carcinoma cells were transduce... | - |
Data from ChEMBL 36 via Core Engine