Compound Detail
CHEMBL6044516
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Basic Information
| ChEMBL ID | CHEMBL6044516 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MAUQWFRCYUDOSP-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
283.3
MW (Da)
2.40
ALogP
5
HBA
2
HBD
76.7
PSA (Ų)
0.77
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | IC50 | 7.15 | 7.15 | 70.1 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase kinase kinase kinase 4 | IC50 | = | 70.1 | nM | 7.15 | MAP4K4 Inhibition Assay: The kinase activity of purified human MAP4K4 kinase dom... | - |
| Mitogen-activated protein kinase kinase kinase kinase 4 | IC50 | = | 70.1 | nM | 7.15 | Inhibition Assay: The kinase activity of purified human MAP4K4 kinase domain was... | - |
Data from ChEMBL 36 via Core Engine