Compound Detail
CHEMBL6048061
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6048061 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SUNPVTURBDMXEP-UHFFFAOYSA-N |
2
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
457.0
MW (Da)
4.77
ALogP
4
HBA
1
HBD
58.6
PSA (Ų)
0.55
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.0
EC50 1 meas. best 9.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | EC50 | 9.2 | 9.2 | 0.6 | 1 |
| Somatostatin receptor type 4 CHEMBL1853 | IC50 | 8.0 | 8.0 | 10.0 | 1 |
| Somatostatin receptor type 1 CHEMBL1917 | IC50 | 4.8 | 4.8 | 15849.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | EC50 | = | 0.631 | nM | 9.2 | Inhibition of Forskolin Stimulated cAMP in Cells Overexpressing SSTR4: This cell... | - |
| Somatostatin receptor type 4 | IC50 | = | 10.0 | nM | 8.0 | SSTR4 I-125 Somatostatin Competition Binding Assay: This membrane-based assay me... | - |
| Somatostatin receptor type 1 | IC50 | = | 15849.0 | nM | 4.8 | SSTR1 I-125 Somatostatin Competition Binding Assay for Selectivity Versus SSTR4:... | - |
Data from ChEMBL 36 via Core Engine