Compound Detail
CHEMBL60518
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Basic Information
| ChEMBL ID | CHEMBL60518 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OOEUHRGMLFVKQO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
418.3
MW (Da)
3.49
ALogP
3
HBA
1
HBD
35.2
PSA (Ų)
0.66
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(4) dopamine receptor CHEMBL219 | Ki | 9.29 | 9.29 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(4) dopamine receptor | Ki | = | 0.51 | nM | 9.29 | Binding affinity towards cloned human Dopamine receptor D4 stably expressed in C... | 8642550 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8642550 | 10.1021/jm9600712 | D(2) dopamine receptor | 1 |
| 8642550 | 10.1021/jm9600712 | D(3) dopamine receptor | 1 |
| 8642550 | 10.1021/jm9600712 | D(4) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine