Compound Detail
CHEMBL6058079
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CN[C@@H]1CCCN(C(=O)c2cc(-c3ccc(C#N)c(F)c3)n(-c3ccc(N4CCC(OC)C4)cc3F)n2)C1
Basic Information
| ChEMBL ID | CHEMBL6058079 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QYKBNQCKAQHEDF-PSDZMVHGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
520.6
MW (Da)
3.74
ALogP
7
HBA
1
HBD
86.4
PSA (Ų)
0.53
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysine-specific histone demethylase 1A CHEMBL6136 | IC50 | 7.47 | 7.47 | 34.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysine-specific histone demethylase 1A | IC50 | = | 34.0 | nM | 7.47 | Biochemical Inhibition Activity Assay: The biochemical inhibition activity of th... | - |
Data from ChEMBL 36 via Core Engine