Compound Detail
CHEMBL605955
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Basic Information
| ChEMBL ID | CHEMBL605955 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHVCBLPINYVBIX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
322.4
MW (Da)
1.96
ALogP
7
HBA
0
HBD
71.2
PSA (Ų)
0.71
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 CHEMBL4980 | Ki | 7.22 | 7.22 | 60.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 | Ki | = | 60.0 | nM | 7.22 | Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expre... | 20043678 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20043678 | 10.1021/jm9015075 | Neuronal acetylcholine receptor subunit alpha-7 | 1 |
| 20043678 | 10.1021/jm9015075 | 5-hydroxytryptamine receptor 3A | 1 |
| 20043678 | 10.1021/jm9015075 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine