Compound Detail

CHEMBL6067487

IVERMECTIN

💊 Approved Drug

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💊 Approved Drug

No structure available

ChEMBL ↗

Basic Information

ChEMBL ID	CHEMBL6067487
Name	IVERMECTIN
Phase	Approved
Structure Type	NONE
Therapeutic	✓ Yes

Known Names

22,23-dihydro c-076b1 22,23-dihydroabamectin 22,23-dihydroavermectin b1 22,23-dihydroavermectin b1a Acarexx Bimectin Bovinet Cardomec Cardotek 30 CD-5024 CD5024 Cevamec +18 more

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Indications

Mechanisms

Drug Information

Molecule Type	Unknown
First Approval	1996
Availability	OTC
Chirality	Single Enantiomer

Routes of Administration

Oral Topical

USAN Stem	-ectin
USAN Year	1979

Mechanism of Action

Mechanism	Action Type	Target	Direct	Efficacy
Glutamate-gated chloride channel modulator	MODULATOR	Glutamate-gated chloride channel	✓	✓
Glutamate-gated chloride channel modulator	MODULATOR	Glutamate-gated chloride channel	✓	✓

Indications

Helminthiasis Lice Infestations Onchocerciasis Rosacea Strongyloidiasis Blepharitis Elephantiasis, Filarial Influenza, Human Malaria Pneumonia Severe Acute Respiratory Syndrome Severe Acute Respiratory Syndrome Acne Vulgaris Anosmia Dengue Dermatitis, Atopic Onchocerciasis, Ocular Severe Dengue Trichuriasis Alcoholism

ATC Classification

D11AX22

ivermectin

Level 1: DERMATOLOGICALS

Level 2: OTHER DERMATOLOGICAL PREPARATIONS

P02CF01

ivermectin

Level 1: ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

Level 2: ANTHELMINTICS

Pharmacokinetic Data

Parameter	Value	Units	Species
F	60.0	%	Homo sapiens

Data from ChEMBL 36 via Core Engine