Compound Detail
CHEMBL6068328
ELTROMBOPAG CHOLINE 💊 Approved Drug
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💊 Approved Drug
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=N\Nc1cccc(-c2cccc(C(=O)[O-])c2)c1O.C[N+](C)(C)CCO
Basic Information
| ChEMBL ID | CHEMBL6068328 |
| Name | ELTROMBOPAG CHOLINE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | XSHFVAAXJHNDKZ-OUFJFOJPSA-M |
| Therapeutic | ✓ Yes |
| Parent Compound | CHEMBL461101 |
| Active Moiety | CHEMBL461101 |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
2
Known Names
4
Indications
1
Mechanisms
Molecular Properties
442.5
MW (Da)
4.56
ALogP
6
HBA
3
HBD
114.6
PSA (Ų)
0.40
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2023 |
| Availability | Prescription |
| Chirality | Achiral |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| Thrombopoietin receptor agonist | AGONIST | Thrombopoietin receptor | ✓ | ✓ |
Indications
Anemia, Aplastic Hepatitis C, Chronic Purpura, Thrombocytopenic, Idiopathic Thrombocytopenia
Drug Warnings
Black Box Warning
General Warning
Data from ChEMBL 36 via Core Engine