Compound Detail
CHEMBL610813
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Basic Information
| ChEMBL ID | CHEMBL610813 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VZNPPUSZNNZBJU-JZIHMUKYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
295.3
MW (Da)
-1.13
ALogP
9
HBA
4
HBD
125.5
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 6.0 | 6.0 | 1000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 1000.0 | nM | 6.0 | Inhibition of hepatitis C virus RNA replication in a subgenomic replicon cell li... | 15664842 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15664842 | 10.1016/j.bmcl.2004.11.020 | Hepatitis C virus | 2 |
| 16033277 | 10.1021/jm048944c | K562 | 2 |
| 16033277 | 10.1021/jm048944c | HT-29 | 1 |
| 16033277 | 10.1021/jm048944c | MCF7 | 1 |
Data from ChEMBL 36 via Core Engine