Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL61537

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Nc1nc(O)c2ncn(C/C=C/CO)c2n1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL61537
Phase Preclinical
Structure Type MOL
InChI Key OPKAHOTXQFICOG-OWOJBTEDSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

221.2
MW (Da)
-0.34
ALogP
7
HBA
3
HBD
110.1
PSA (Ų)
0.61
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C9H11N5O2
MW 221.22
Aromatic Rings 2
Heavy Atoms 16
NP-Likeness -0.14

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
2848125 10.1021/jm00120a010 DNA polymerase catalytic subunit 5
2848125 10.1021/jm00120a010 Oryctolagus cuniculus 2
3027333 10.1021/jm00384a033 Human alphaherpesvirus 1 2
3027333 10.1021/jm00384a033 Human alphaherpesvirus 2 2
2848125 10.1021/jm00120a010 Unchecked 1
1992143 10.1021/jm00105a064 L1210 1

Data from ChEMBL 36 via Core Engine