Compound Detail
CHEMBL6205
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6205 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FUVJGBQDHCCGCD-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
399.4
MW (Da)
3.08
ALogP
5
HBA
2
HBD
76.3
PSA (Ų)
0.51
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C (PKC) CHEMBL2094266 | IC50 | 6.89 | 6.89 | 130.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.85 | 4.85 | 14200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C (PKC) | IC50 | = | 130.0 | nM | 6.89 | Inhibition of protein kinase C (PKC) in rat brain | 1552513 |
| Unchecked | IC50 | = | 14200.0 | nM | 4.85 | Inhibition of c-AMP dependent protein kinase A (PKA) in bovine heart | 1552513 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1552513 | 10.1021/jm00084a004 | Protein kinase C (PKC) | 1 |
| 1552513 | 10.1021/jm00084a004 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine