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Compound Detail

CHEMBL63902

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N[C@@H](CC(=O)NO)C(=O)O

Basic Information

ChEMBL ID CHEMBL63902
Phase Preclinical
Structure Type MOL
InChI Key ZBYVTTSIVDYQSO-REOHCLBHSA-N
0
Targets
2
Activities
2
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

148.1
MW (Da)
-1.71
ALogP
4
HBA
4
HBD
112.7
PSA (Ų)
0.28
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C4H8N2O4
MW 148.12
Aromatic Rings 0
Heavy Atoms 10
NP-Likeness 0.69

Activity Summary

IC50 1 meas.
Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
19791805 10.1021/jm900775q Unchecked 5
19791805 10.1021/jm900775q Serine racemase 4
22754 10.1021/jm00199a008 Asparagine synthetase [glutamine-hydrolyzing] 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
- 10.6019/CHEMBL4808148 Histone deacetylase 6 2
12798312 10.1016/s0960-894x(03)00407-4 Glutamate carboxypeptidase 2 1
19791805 10.1021/jm900775q L-serine dehydratase/L-threonine deaminase 1
19791805 10.1021/jm900775q Alanine racemase 1
- 10.21203/rs.3.rs-23951/v1 SARS-CoV-2 1
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1

Data from ChEMBL 36 via Core Engine