Compound Detail
CHEMBL67436
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL67436 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KSELTIXXASIVDL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
313.3
MW (Da)
4.07
ALogP
4
HBA
0
HBD
40.6
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-derived growth factor receptor CHEMBL2095189 | IC50 | 8.3 | 8.3 | 5.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-derived growth factor receptor | IC50 | = | 5.0 | nM | 8.3 | Inhibition of human PDGF receptor phosphorylation; 0.003-0.005 | 8035419 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8035419 | 10.1021/jm00040a003 | Platelet-derived growth factor receptor | 1 |
| 8035419 | 10.1021/jm00040a003 | Epidermal growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine