Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL69063

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COC(=O)c1cc2c([nH]1)C(=O)C=C1C2C(C)CN1C(=O)c1cc2cc(OC)c(OC)c(OC)c2[nH]1

Basic Information

ChEMBL ID CHEMBL69063
Phase Preclinical
Structure Type MOL
InChI Key HEGVEVMSAJPKJI-UHFFFAOYSA-N
0
Targets
2
Activities
1
Assay Types
1
PK Parameters
3
Publications
0
Known Names

Molecular Properties

479.5
MW (Da)
3.26
ALogP
7
HBA
2
HBD
123.0
PSA (Ų)
0.54
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H25N3O7
MW 479.49
Aromatic Rings 3
Heavy Atoms 35
NP-Likeness 0.10

Activity Summary

IC50 2 meas.

Pharmacokinetic Data

Parameter Value Units Species
T1/2 1000.0 hr -

Literature References

PubMed DOI Target Context # Activities
- 10.1016/0960-894X(96)00388-5 HeLa 2
- 10.1016/0960-894X(96)00388-5 ADMET 1
- 10.1016/0960-894X(96)00388-5 Sarcoma-180 1

Data from ChEMBL 36 via Core Engine