Compound Detail
CHEMBL69184
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Basic Information
| ChEMBL ID | CHEMBL69184 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NITZEITXMRNCEG-HTQZYQBOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
276.3
MW (Da)
0.65
ALogP
7
HBA
3
HBD
119.0
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adenylate cyclase type 5 CHEMBL3189 | IC50 | 6.22 | 6.22 | 600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adenylate cyclase type 5 | IC50 | = | 600.0 | nM | 6.22 | Inhibitory activity against recombinant human adenylate cyclase 5 expressed in H... | 12747789 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12747789 | 10.1021/jm0205604 | Adenylate cyclase type 5 | 1 |
Data from ChEMBL 36 via Core Engine