Compound Detail
CHEMBL70725
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Basic Information
| ChEMBL ID | CHEMBL70725 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VVXNEXXFHWJKLS-ZYOSVBKOSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
310.5
MW (Da)
1.94
ALogP
4
HBA
4
HBD
75.3
PSA (Ų)
0.53
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.66 | 6.01 | 220.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 220.0 | nM | 6.66 | Inhibition of partially purified soluble aminopeptidase from rat brain | 3184127 |
| Unchecked | IC50 | = | 4400.0 | nM | 5.36 | Inhibition of partially purified soluble aminopeptidase from rat brain | 3184127 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3184127 | 10.1021/jm00119a023 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine