Compound Detail
CHEMBL72157
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Basic Information
| ChEMBL ID | CHEMBL72157 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IFLWVSHRWAIVQF-IZJGZUANSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
235.2
MW (Da)
0.51
ALogP
3
HBA
3
HBD
100.6
PSA (Ų)
0.71
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.6 | 7.6 | 25.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 25.0 | nM | 7.6 | Antagonistic activity against phospholipase D (PLD) was determined in adult rat ... | 10411492 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10411492 | 10.1021/jm990128v | Unchecked | 2 |
| 10411492 | 10.1021/jm990128v | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | 1 |
Data from ChEMBL 36 via Core Engine