Compound Detail
CHEMBL78739
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Basic Information
| ChEMBL ID | CHEMBL78739 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IPIMWLRTLPSLPA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
284.5
MW (Da)
1.48
ALogP
4
HBA
4
HBD
48.1
PSA (Ų)
0.41
QED
0
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L1210 CHEMBL386 | Ki | 5.1 | 5.1 | 7900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L1210 | Ki | = | 7900.0 | nM | 5.1 | In vitro inhibition of uptake [3H]-spermidine in L1210 (murine leukemia) cells. | 8691443 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11170633 | 10.1021/jm000277+ | Rattus norvegicus | 41 |
| 8691443 | 10.1021/jm950827h | L1210 | 1 |
Data from ChEMBL 36 via Core Engine