Compound Detail
CHEMBL80774
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Basic Information
| ChEMBL ID | CHEMBL80774 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBZLAMVCSTTXNG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
439.6
MW (Da)
6.73
ALogP
3
HBA
0
HBD
18.8
PSA (Ų)
0.51
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.88
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-activating factor receptor CHEMBL250 | IC50 | 4.88 | 4.88 | 13100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-activating factor receptor | IC50 | = | 13100.0 | nM | 4.88 | Inhibition of [3H]PAF binding to human platelet activating factor receptor | 7830265 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7830265 | 10.1021/jm00002a004 | Abelson 8.1 | 3 |
| 7830265 | 10.1021/jm00002a004 | Platelet-activating factor receptor | 1 |
Data from ChEMBL 36 via Core Engine