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Compound Detail

CHEMBL816

ETHYLENEDIAMINE
🧪 Phase III
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🧪 Phase III

Basic Information

ChEMBL ID CHEMBL816
Name ETHYLENEDIAMINE
Phase Phase III
Structure Type MOL
InChI Key PIICEJLVQHRZGT-UHFFFAOYSA-N

Known Names

Edamina Edamine Ethylene diamine Ethylenediamine PB-05721 PB05721
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
12
Publications
6
Known Names
2
Indications

Molecular Properties

60.1
MW (Da)
-1.10
ALogP
2
HBA
2
HBD
52.0
PSA (Ų)
0.40
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral

Flags

Natural Product

Extended Properties

Molecular Formula C2H8N2
MW 60.10
Aromatic Rings 0
Heavy Atoms 4
NP-Likeness 0.34

Indications

Chemical and Drug Induced Liver Injury Prostatic Neoplasms

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
27451257 10.1016/j.ejmech.2016.04.069 No relevant target 11
19648006 10.1016/j.bmcl.2009.07.086 J774 6
31901381 10.1016/j.bmcl.2019.126903 No relevant target 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
12699746 10.1016/s0960-894x(03)00183-5 Protein farnesyltransferase 1
12127537 10.1016/s0960-894x(02)00365-7 Matrix metalloproteinase-9 1
19648006 10.1016/j.bmcl.2009.07.086 Mycobacterium tuberculosis 1
19581101 10.1016/j.bmc.2009.06.023 Staphylococcus aureus 1
19581101 10.1016/j.bmc.2009.06.023 Bacillus subtilis 1
19581101 10.1016/j.bmc.2009.06.023 Serratia marcescens 1
19581101 10.1016/j.bmc.2009.06.023 Pseudomonas aeruginosa 1
19581101 10.1016/j.bmc.2009.06.023 Escherichia coli 1

Data from ChEMBL 36 via Core Engine