Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL84963

BENZOTRIAZOLE
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
c1ccc2[nH]nnc2c1

Basic Information

ChEMBL ID CHEMBL84963
Name BENZOTRIAZOLE
Phase Preclinical
Structure Type MOL
InChI Key QRUDEWIWKLJBPS-UHFFFAOYSA-N
0
Targets
3
Activities
1
Assay Types
0
PK Parameters
15
Publications
0
Known Names

Molecular Properties

119.1
MW (Da)
0.96
ALogP
2
HBA
1
HBD
41.6
PSA (Ų)
0.56
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C6H5N3
MW 119.13
Aromatic Rings 2
Heavy Atoms 9
NP-Likeness -1.79

Activity Summary

IC50 3 meas.

Literature References

PubMed DOI Target Context # Activities
- 10.1039/C3MD00117B Prolyl hydroxylase EGLN3 3
22616902 10.1021/jm300260v No relevant target 2
23750537 10.1021/jm4001488 5'-AMP-activated protein kinase catalytic subunit alpha-2 2
28789912 10.1016/j.bmc.2017.07.045 P2Y purinoceptor 12 2
2167983 10.1021/jm00171a043 No relevant target 1
21925773 10.1016/j.ejmech.2011.08.044 Indoleamine 2,3-dioxygenase 1 1
22616902 10.1021/jm300260v Indoleamine 2,3-dioxygenase 1 1
23750537 10.1021/jm4001488 Unchecked 1
26048799 10.1016/j.bmcl.2015.05.020 HEK293 1
26048799 10.1016/j.bmcl.2015.05.020 Unchecked 1
26048799 10.1016/j.bmcl.2015.05.020 MCF7 1
26048799 10.1016/j.bmcl.2015.05.020 MDA-MB-231 1
26048799 10.1016/j.bmcl.2015.05.020 NAD(P)H dehydrogenase [quinone] 1 1
27750152 10.1016/j.ejmech.2016.10.005 Sodium/hydrogen exchanger 1 1
33557523 10.1021/acs.jmedchem.0c01968 Indoleamine 2,3-dioxygenase 1 1

Data from ChEMBL 36 via Core Engine