Compound Detail
CHEMBL88476
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Basic Information
| ChEMBL ID | CHEMBL88476 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZOFRRNUENOHELM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
115.2
MW (Da)
0.56
ALogP
2
HBA
1
HBD
43.1
PSA (Ų)
0.55
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cytosol aminopeptidase CHEMBL3965 | Ki | 7.22 | 7.22 | 60.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytosol aminopeptidase | Ki | = | 60.0 | nM | 7.22 | Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | 12801228 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12801228 | 10.1021/jm030795v | Cytosol aminopeptidase | 1 |
Data from ChEMBL 36 via Core Engine