Compound Detail
CHEMBL892
UFIPRAZOLE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL892 |
| Name | UFIPRAZOLE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | XURCIPRUUASYLR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
3
Known Names
Molecular Properties
329.4
MW (Da)
3.88
ALogP
5
HBA
1
HBD
60.0
PSA (Ų)
0.72
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
EC50 1 meas. best 5.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bombesin receptor subtype-3 CHEMBL4080 | EC50 | 5.41 | 5.41 | 3900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bombesin receptor subtype-3 | EC50 | = | 3900.0 | nM | 5.41 | Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduc... | 18818070 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8523404 | 10.1021/jm00025a008 | Unchecked | 3 |
| 18818070 | 10.1016/j.bmcl.2008.09.033 | Bombesin receptor subtype-3 | 2 |
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| - | 10.6019/CHEMBL4808148 | Histone deacetylase 6 | 2 |
| 9599229 | 10.1021/jm970165r | Helicobacter pylori | 1 |
| 9599229 | 10.1021/jm970165r | No relevant target | 1 |
| - | 10.21203/rs.3.rs-23951/v1 | SARS-CoV-2 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine