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Compound Detail

CHEMBL89416

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CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@H](C(=O)NC(Cc1c[nH]cn1)C(=O)O)[C@@H](C)CC

Basic Information

ChEMBL ID CHEMBL89416
Phase Preclinical
Structure Type MOL
InChI Key FCHVBJPUWRSWLL-AJPQGBEXSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

798.9
MW (Da)
0.82
ALogP
9
HBA
9
HBD
277.9
PSA (Ų)
0.07
QED
2
Ro5 Violations
24
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C39H58N8O10
MW 798.94
Aromatic Rings 2
Heavy Atoms 57
NP-Likeness 0.09

Literature References

PubMed DOI Target Context # Activities
8410970 10.1021/jm00070a001 Endothelin-1 receptor 1
8410970 10.1021/jm00070a001 Endothelin receptor type B 1

Data from ChEMBL 36 via Core Engine