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Compound Detail

CHEMBL98733

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CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](/C=C/[N+](=O)[O-])CCC(N)=O

Basic Information

ChEMBL ID CHEMBL98733
Phase Preclinical
Structure Type MOL
InChI Key OSGQRUSDCFSVHU-DOAZHDKUSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

567.6
MW (Da)
2.60
ALogP
7
HBA
4
HBD
182.8
PSA (Ų)
0.18
QED
1
Ro5 Violations
16
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C29H37N5O7
MW 567.64
Aromatic Rings 2
Heavy Atoms 41
NP-Likeness -0.02

Literature References

PubMed DOI Target Context # Activities
9667970 10.1021/jm980068d HeLa 2
9667970 10.1021/jm980068d Human rhinovirus A protease 1
9667970 10.1021/jm980068d Human rhinovirus sp. 1

Data from ChEMBL 36 via Core Engine