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Compound Detail

CHEMBL99014

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CO[C@@H](Cc1ccccc1)[C@@H](C)/C=C(C)/C=C/[C@H](NC(C)=O)[C@H](C)C(=O)N1C[C@H](O[Si](C(C)C)(C(C)C)C(C)C)C[C@@H]1C(=O)O

Basic Information

ChEMBL ID CHEMBL99014
Phase Preclinical
Structure Type MOL
InChI Key LPBZOVMAJWYNPJ-HQFMBDCXSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

643.0
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C36H58N2O6Si
MW 642.95

Literature References

PubMed DOI Target Context # Activities
14611855 10.1016/s0960-894x(03)00588-2 Protein phosphatase 1B 1
14611855 10.1016/s0960-894x(03)00588-2 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 1
14611855 10.1016/s0960-894x(03)00588-2 Unchecked 1

Data from ChEMBL 36 via Core Engine