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Target Snapshot

CHEMBL1075058 Target Snapshot

Chemoattractant receptor-homologous molecule expressed on Th2 cells · SINGLE PROTEIN · Cavia porcellus

44Compounds
6Assays
0Approved Drugs
17.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q56D28. Use UniProt Q56D28 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q56D28 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Protein anchor
Chemoattractant receptor-homologous molecule expressed on Th2 cells

Chemoattractant receptor-homologous molecule expressed on Th2 cells

Review this target as Chemoattractant receptor-homologous molecule expressed on Th2 cells, mapped to UniProt Q56D28. Sequence length is 391 aa.

Protein source · UniProt accession via ChEMBL component mapping
UniProt Q56D28 Protein 391 aa
Open protein block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Chemoattractant receptor-homologous molecule expressed on Th2 cells as ChEMBL target CHEMBL1075058, mapped to UniProt Q56D28. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Chemoattractant receptor-homologous molecule expressed on Th2 cells
SINGLE PROTEIN · Cavia porcellus
As of 2026-09-14
ChEMBL target ID
CHEMBL1075058
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q56D28
Chemoattractant receptor-homologous molecule expressed on Th2 cells
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelChemoattractant receptor-homologous molecule expressed on Th2 cells
UniProt AccessionQ56D28
Component TypeProtein
Sequence Length391 aa

Chemoattractant receptor-homologous molecule expressed on Th2 cells

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Chemoattractant receptor-homologous molecule expressed on Th2 cells, mapped to UniProt Q56D28. Sequence length is 391 aa.

Mapped IDQ56D28
Review nameChemoattractant receptor-homologous molecule expressed on Th2 cells
OrganismCavia porcellus
Assay Mix

Activity Type Distribution

IC5017.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL589973 8.52 IC50 3.0 Preclinical
CHEMBL1941129 7.77 IC50 17.0 Preclinical
CHEMBL1941128 7.75 IC50 18.0 Preclinical
CHEMBL1088284 7.54 IC50 29.0 Preclinical
CHEMBL1941127 7.28 IC50 52.0 Preclinical
CHEMBL1778639 7.2 IC50 63.0 Preclinical
CHEMBL1941126 7.0 IC50 99.0 Preclinical
CHEMBL1941123 6.89 IC50 128.0 Preclinical
CHEMBL1941117 6.83 IC50 147.0 Preclinical
CHEMBL1941121 6.68 IC50 211.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
4
6.0
4
6.5
3
7.0
3
7.5
0
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

6
Total Assays
15
Tested Compounds
2
Assay Types
Binding — 4 assays, 15 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 13 6.9
single protein format 2 2 7.4
Functional — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine