Thymidine kinase · SINGLE PROTEIN · Macacine herpesvirus 1
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As of 2026-09-14Protein identity stays anchored to UniProt A3RLP8. Use UniProt A3RLP8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A3RLP8 as the stable identity anchor, then attach disease evidence before program review.
Thymidine kinase
Review this target as Thymidine kinase, mapped to UniProt A3RLP8. Sequence length is 370 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Thymidine kinase as ChEMBL target CHEMBL1075062, mapped to UniProt A3RLP8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Thymidine kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Macacine herpesvirus 1 |
| UniProt | A3RLP8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thymidine kinase |
| UniProt Accession | A3RLP8 |
| Component Type | Protein |
| Sequence Length | 370 aa |
Thymidine kinase
Review this target as Thymidine kinase, mapped to UniProt A3RLP8. Sequence length is 370 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL318153 | 6.82 | IC50 | 150.0 | Clinical |
| CHEMBL441732 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL788 | 5.82 | IC50 | 1500.0 | Approved |
| CHEMBL1129 | 5.7 | IC50 | 2000.0 | Approved |
| CHEMBL408518 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL405761 | 5.46 | IC50 | 3500.0 | Preclinical |
| CHEMBL52609 | 5.39 | IC50 | 4100.0 | Clinical |
| CHEMBL221982 | 5.38 | IC50 | 4200.0 | Preclinical |
| CHEMBL406254 | 4.94 | IC50 | 11500.0 | Preclinical |
| CHEMBL261850 | 4.82 | IC50 | 15000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 17 | 5.3 |