Protein tyrosine phosphatase type IVA 2 · SINGLE PROTEIN · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q12974. Use UniProt Q12974 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q12974 as the stable identity anchor, then attach disease evidence before program review.
Protein tyrosine phosphatase type IVA 2
Review this target as Protein tyrosine phosphatase type IVA 2, mapped to UniProt Q12974. Sequence length is 167 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein tyrosine phosphatase type IVA 2 as ChEMBL target CHEMBL1075105, mapped to UniProt Q12974. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Protein tyrosine phosphatase type IVA 2 is the right protein anchor across sources, using UniProt Q12974 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Protein tyrosine phosphatase type IVA 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q12974 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein tyrosine phosphatase type IVA 2 |
| UniProt Accession | Q12974 |
| Component Type | Protein |
| Sequence Length | 167 aa |
Protein tyrosine phosphatase type IVA 2
Review this target as Protein tyrosine phosphatase type IVA 2, mapped to UniProt Q12974. Sequence length is 167 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4445621 | 7.28 | IC50 | 52.0 | Preclinical |
| CHEMBL3393171 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL55 | 6.52 | IC50 | 300.0 | Approved |
| CHEMBL1088572 | 6.5 | IC50 | 314.0 | Preclinical |
| CHEMBL3393148 | 4.5 | IC50 | 31400.0 | Preclinical |
| CHEMBL3393149 | 4.16 | IC50 | 69400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 10 | 5.4 |
| assay format | 4 | 2 | 6.8 |
| cell-based format | 1 | 0 | — |