Dual specificity tyrosine-phosphorylation-regulated kinase 4 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9NR20. Use UniProt Q9NR20 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NR20 as the stable identity anchor, then attach disease evidence before program review.
Dual specificity tyrosine-phosphorylation-regulated kinase 4
Review this target as Dual specificity tyrosine-phosphorylation-regulated kinase 4, mapped to UniProt Q9NR20. Sequence length is 520 aa.
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This review treats Dual specificity tyrosine-phosphorylation-regulated kinase 4 as ChEMBL target CHEMBL1075115, mapped to UniProt Q9NR20. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NR20 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| UniProt Accession | Q9NR20 |
| Component Type | Protein |
| Sequence Length | 520 aa |
Dual specificity tyrosine-phosphorylation-regulated kinase 4
Review this target as Dual specificity tyrosine-phosphorylation-regulated kinase 4, mapped to UniProt Q9NR20. Sequence length is 520 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4784318 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL1965660 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL1981079 | 7.9 | Ki | 12.59 | Preclinical |
| CHEMBL4873449 | 7.57 | IC50 | 26.8 | Preclinical |
| CHEMBL5400230 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL3103192 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL1978448 | 7.4 | Ki | 39.81 | Preclinical |
| CHEMBL5438158 | 7.33 | IC50 | 47.0 | Preclinical |
| CHEMBL5405059 | 7.32 | IC50 | 48.0 | Preclinical |
| CHEMBL1964290 | 7.3 | Ki | 50.12 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 78 | 209 | 6.0 |
| assay format | 10 | 2 | 5.1 |
| cell-based format | 3 | 24 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 88 | 5.9 |