Rhodopsin kinase GRK7 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q8WTQ7. Use UniProt Q8WTQ7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8WTQ7 as the stable identity anchor, then attach disease evidence before program review.
Rhodopsin kinase GRK7
Review this target as Rhodopsin kinase GRK7, mapped to UniProt Q8WTQ7. Sequence length is 553 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Rhodopsin kinase GRK7 as ChEMBL target CHEMBL1075133, mapped to UniProt Q8WTQ7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Rhodopsin kinase GRK7 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8WTQ7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Rhodopsin kinase GRK7 |
| UniProt Accession | Q8WTQ7 |
| Component Type | Protein |
| Sequence Length | 553 aa |
Rhodopsin kinase GRK7
Review this target as Rhodopsin kinase GRK7, mapped to UniProt Q8WTQ7. Sequence length is 553 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.07 | Kd | 0.86 | Preclinical |
| CHEMBL388978 | 8.34 | IC50 | 4.56 | Preclinical |
| CHEMBL4877302 | 8.19 | IC50 | 6.4 | Preclinical |
| CHEMBL603469 | 8.14 | Kd | 7.2 | Clinical |
| CHEMBL4854871 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL4847703 | 7.44 | IC50 | 36.0 | Preclinical |
| CHEMBL608533 | 7.32 | Kd | 48.0 | Approved |
| CHEMBL450786 | 7.21 | Kd | 61.0 | Preclinical |
| CHEMBL60254 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL535 | 6.75 | Kd | 180.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 128 | 32 | 6.6 |
| assay format | 17 | 4 | 5.0 |
| cell-based format | 9 | 0 | — |