Glucokinase regulatory protein · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-15Protein identity stays anchored to UniProt Q14397. Use UniProt Q14397 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q14397 as the stable identity anchor, then attach disease evidence before program review.
Glucokinase regulatory protein
Review this target as Glucokinase regulatory protein, mapped to UniProt Q14397. Sequence length is 625 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glucokinase regulatory protein as ChEMBL target CHEMBL1075152, mapped to UniProt Q14397. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glucokinase regulatory protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q14397 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glucokinase regulatory protein |
| UniProt Accession | Q14397 |
| Component Type | Protein |
| Sequence Length | 625 aa |
Glucokinase regulatory protein
Review this target as Glucokinase regulatory protein, mapped to UniProt Q14397. Sequence length is 625 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3746243 | 8.82 | Kd | 1.5 | Preclinical |
| CHEMBL3746243 | 8.42 | IC50 | 3.8 | Preclinical |
| CHEMBL3114185 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL3745887 | 8.38 | Kd | 4.2 | Preclinical |
| CHEMBL3237987 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3237981 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3237986 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3745887 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3746444 | 8.18 | Kd | 6.6 | Preclinical |
| CHEMBL3746034 | 8.07 | Kd | 8.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 15 | 86 | 6.8 |