Serine/threonine-protein kinase haspin · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q8TF76. Use UniProt Q8TF76 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TF76 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase haspin
Review this target as Serine/threonine-protein kinase haspin, mapped to UniProt Q8TF76. Sequence length is 798 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase haspin as ChEMBL target CHEMBL1075163, mapped to UniProt Q8TF76. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase haspin is the right protein anchor across sources, using UniProt Q8TF76 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase haspin |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TF76 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase haspin |
| UniProt Accession | Q8TF76 |
| Component Type | Protein |
| Sequence Length | 798 aa |
Serine/threonine-protein kinase haspin
Review this target as Serine/threonine-protein kinase haspin, mapped to UniProt Q8TF76. Sequence length is 798 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5199572 | 10.72 | Kd | 0.019 | Preclinical |
| CHEMBL5574055 | 9.81 | IC50 | 0.155 | Preclinical |
| CHEMBL5194339 | 9.38 | Kd | 0.42 | Preclinical |
| CHEMBL5440655 | 9.26 | Kd | 0.55 | Preclinical |
| CHEMBL4791276 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL5178368 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5186093 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5201780 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5563528 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4064608 | 8.4 | IC50 | 4.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 175 | 140 | 6.7 |
| assay format | 49 | 61 | 6.7 |
| cell-based format | 34 | 3 | 9.0 |
| subcellular format | 1 | 1 | 6.1 |
| tissue-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 3 | 5.9 |
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 18 | 6.5 |