Serine/threonine-protein kinase TAO2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UL54. Use UniProt Q9UL54 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UL54 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase TAO2
Review this target as Serine/threonine-protein kinase TAO2, mapped to UniProt Q9UL54. Sequence length is 1235 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase TAO2 as ChEMBL target CHEMBL1075195, mapped to UniProt Q9UL54. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase TAO2 is the right protein anchor across sources, using UniProt Q9UL54 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase TAO2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UL54 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase TAO2 |
| UniProt Accession | Q9UL54 |
| Component Type | Protein |
| Sequence Length | 1235 aa |
Serine/threonine-protein kinase TAO2
Review this target as Serine/threonine-protein kinase TAO2, mapped to UniProt Q9UL54. Sequence length is 1235 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 8.45 | IC50 | 3.54 | Preclinical |
| CHEMBL3688339 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL388978 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL574738 | 7.36 | Kd | 44.0 | Preclinical |
| CHEMBL445813 | 7.3 | Kd | 50.0 | Clinical |
| CHEMBL4063500 | 7.08 | IC50 | 84.0 | Preclinical |
| CHEMBL2334586 | 7.05 | IC50 | 89.0 | Preclinical |
| CHEMBL4554938 | 7.0 | Kd | 100.0 | Preclinical |
| CHEMBL4554938 | 6.87 | IC50 | 134.0 | Preclinical |
| CHEMBL558752 | 6.85 | Kd | 140.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 161 | 38 | 6.2 |
| assay format | 30 | 6 | 5.6 |
| cell-based format | 25 | 1 | 7.1 |
| subcellular format | 12 | 14 | 5.7 |