PhzR · SINGLE PROTEIN · Pseudomonas aeruginosa
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As of 2026-09-14Protein identity stays anchored to UniProt Q9RMS5. Use UniProt Q9RMS5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9RMS5 as the stable identity anchor, then attach disease evidence before program review.
LuxR family transcriptional regulator
Review this target as PhzR, mapped to UniProt Q9RMS5. ChEMBL maps the protein component as LuxR family transcriptional regulator. Sequence length is 237 aa.
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This review treats PhzR as ChEMBL target CHEMBL1075213, mapped to UniProt Q9RMS5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | PhzR |
| Target Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa |
| UniProt | Q9RMS5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | LuxR family transcriptional regulator |
| UniProt Accession | Q9RMS5 |
| Component Type | Protein |
| Sequence Length | 237 aa |
LuxR family transcriptional regulator
Review this target as PhzR, mapped to UniProt Q9RMS5. ChEMBL maps the protein component as LuxR family transcriptional regulator. Sequence length is 237 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL8755 | 8.3 | EC50 | 5.0 | Preclinical |
| CHEMBL8799 | 8.22 | EC50 | 6.0 | Preclinical |
| CHEMBL463321 | 7.96 | EC50 | 11.0 | Preclinical |
| CHEMBL8483 | 7.83 | EC50 | 14.74 | Preclinical |
| CHEMBL259441 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL8463 | 7.11 | EC50 | 78.0 | Preclinical |
| CHEMBL1823931 | 7.09 | EC50 | 80.46 | Preclinical |
| CHEMBL259439 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL265683 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL258913 | 6.75 | IC50 | 180.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 9 | 6.2 |
| single protein format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 10 | 7.4 |