5'-nucleotidase · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P21588. Use UniProt P21588 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21588 as the stable identity anchor, then attach disease evidence before program review.
5'-nucleotidase
Review this target as 5'-nucleotidase, mapped to UniProt P21588. Sequence length is 576 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5'-nucleotidase as ChEMBL target CHEMBL1075214, mapped to UniProt P21588. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 5'-nucleotidase is the right protein anchor across sources, using UniProt P21588 as the stable mapping.
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| Preferred Name | 5'-nucleotidase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P21588 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5'-nucleotidase |
| UniProt Accession | P21588 |
| Component Type | Protein |
| Sequence Length | 576 aa |
5'-nucleotidase
Review this target as 5'-nucleotidase, mapped to UniProt P21588. Sequence length is 576 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4452072 | 9.13 | Ki | 0.746 | Preclinical |
| CHEMBL598619 | 9.06 | Ki | 0.87 | Preclinical |
| CHEMBL14830 | 9.04 | Ki | 0.91 | Preclinical |
| CHEMBL4443977 | 8.44 | Ki | 3.67 | Preclinical |
| CHEMBL2408703 | 8.33 | Ki | 4.7 | Preclinical |
| CHEMBL4483379 | 7.86 | Ki | 13.9 | Preclinical |
| CHEMBL3606064 | 7.83 | Ki | 14.8 | Preclinical |
| CHEMBL4585872 | 7.82 | Ki | 15.1 | Preclinical |
| CHEMBL4475460 | 7.73 | Ki | 18.6 | Preclinical |
| CHEMBL4443094 | 7.73 | Ki | 18.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 18 | 109 | 6.2 |
| single protein format | 8 | 22 | 5.7 |
| assay format | 2 | 0 | — |