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Target Snapshot

CHEMBL1075220 Target Snapshot

Dehydrogenase/reductase SDR family member 9 · SINGLE PROTEIN · Rattus norvegicus

21Compounds
4Assays
1Approved Drugs
21.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q8VD48. Use UniProt Q8VD48 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q8VD48 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Dehydrogenase/reductase SDR family member 9 as ChEMBL target CHEMBL1075220, mapped to UniProt Q8VD48. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Dehydrogenase/reductase SDR family member 9
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL1075220
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q8VD48
Dehydrogenase/reductase SDR family member 9
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Dehydrogenase/reductase SDR family member 9 is the right protein anchor across sources, using UniProt Q8VD48 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelDehydrogenase/reductase SDR family member 9
UniProt AccessionQ8VD48
Component TypeProtein
Sequence Length319 aa

Dehydrogenase/reductase SDR family member 9

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Dehydrogenase/reductase SDR family member 9, mapped to UniProt Q8VD48. Sequence length is 319 aa.

Mapped IDQ8VD48
Review nameDehydrogenase/reductase SDR family member 9
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC5021.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL396182 5.24 IC50 5800.0 Preclinical
CHEMBL236237 5.0 IC50 10000.0 Preclinical
CHEMBL236238 4.75 IC50 18000.0 Preclinical
CHEMBL398087 4.47 IC50 34000.0 Preclinical
CHEMBL236030 4.16 IC50 70000.0 Preclinical
CHEMBL397792 4.0 IC50 100000.0 Preclinical
CHEMBL413980 4.0 IC50 100000.0 Preclinical
CHEMBL521 4.0 IC50 100000.0 Approved
Distribution

pChEMBL Value Distribution

2
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
14
Tested Compounds
1
Assay Types
Binding — 4 assays, 14 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 4 14 4.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine