Use UniProt P29598 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1075245 Target Snapshot
Urokinase-type plasminogen activator · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P29598. Use UniProt P29598 as the stable identity anchor, then attach disease evidence before program review.
Urokinase-type plasminogen activator
Review this target as Urokinase-type plasminogen activator, mapped to UniProt P29598. Sequence length is 432 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Urokinase-type plasminogen activator as ChEMBL target CHEMBL1075245, mapped to UniProt P29598. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Urokinase-type plasminogen activator is the right protein anchor across sources, using UniProt P29598 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Urokinase-type plasminogen activator |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P29598 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Urokinase-type plasminogen activator |
| UniProt Accession | P29598 |
| Component Type | Protein |
| Sequence Length | 432 aa |
Urokinase-type plasminogen activator
How to read this target
Review this target as Urokinase-type plasminogen activator, mapped to UniProt P29598. Sequence length is 432 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL393591 | 7.71 | IC50 | 19.5 | Preclinical |
| CHEMBL393979 | 7.61 | IC50 | 24.5 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 2 | 7.7 |