Geranylgeranyl pyrophosphate synthase BTS1 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-14Protein identity stays anchored to UniProt Q12051. Use UniProt Q12051 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q12051 as the stable identity anchor, then attach disease evidence before program review.
Geranylgeranyl pyrophosphate synthase BTS1
Review this target as Geranylgeranyl pyrophosphate synthase BTS1, mapped to UniProt Q12051. Sequence length is 335 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Geranylgeranyl pyrophosphate synthase BTS1 as ChEMBL target CHEMBL1075251, mapped to UniProt Q12051. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Geranylgeranyl pyrophosphate synthase BTS1 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | Q12051 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Geranylgeranyl pyrophosphate synthase BTS1 |
| UniProt Accession | Q12051 |
| Component Type | Protein |
| Sequence Length | 335 aa |
Geranylgeranyl pyrophosphate synthase BTS1
Review this target as Geranylgeranyl pyrophosphate synthase BTS1, mapped to UniProt Q12051. Sequence length is 335 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL192017 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL192017 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL213490 | 7.52 | Ki | 30.0 | Preclinical |
| CHEMBL262616 | 7.52 | Ki | 30.0 | Preclinical |
| CHEMBL260880 | 7.22 | Ki | 60.0 | Preclinical |
| CHEMBL213490 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL262616 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL259026 | 7.1 | Ki | 80.0 | Preclinical |
| CHEMBL411274 | 6.96 | Ki | 110.0 | Preclinical |
| CHEMBL319144 | 6.89 | Ki | 130.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 8 | 7.0 |