Adenosine receptor A3 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q61618. Use UniProt Q61618 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q61618 as the stable identity anchor, then attach disease evidence before program review.
Adenosine receptor A3
Review this target as Adenosine receptor A3, mapped to UniProt Q61618. Sequence length is 319 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenosine receptor A3 as ChEMBL target CHEMBL1075269, mapped to UniProt Q61618. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenosine receptor A3 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q61618 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosine receptor A3 |
| UniProt Accession | Q61618 |
| Component Type | Protein |
| Sequence Length | 319 aa |
Adenosine receptor A3
Review this target as Adenosine receptor A3, mapped to UniProt Q61618. Sequence length is 319 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL119709 | 10.06 | Ki | 0.087 | Preclinical |
| CHEMBL431733 | 9.82 | EC50 | 0.15 | Clinical |
| CHEMBL431733 | 9.74 | Ki | 0.18 | Clinical |
| CHEMBL3407783 | 9.6 | EC50 | 0.25 | Preclinical |
| CHEMBL3407774 | 9.49 | EC50 | 0.32 | Preclinical |
| CHEMBL5196916 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL3407784 | 9.22 | EC50 | 0.6 | Preclinical |
| CHEMBL27376 | 9.1 | Ki | 0.8 | Preclinical |
| CHEMBL2064658 | 9.09 | Ki | 0.82 | Preclinical |
| CHEMBL402574 | 9.07 | Ki | 0.85 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 24 | 132 | 7.2 |
| cell membrane format | 5 | 25 | 8.5 |
| single protein format | 3 | 1 | 5.2 |
| assay format | 1 | 11 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 10 | 8.7 |
| single protein format | 1 | 0 | — |