DMS-53 · CELL-LINE · Homo sapiens
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DMS-53
Review this target as DMS-53.
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This review treats DMS-53 as ChEMBL target CHEMBL1075434. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | DMS-53 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as DMS-53.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4297458 | 9.54 | IC50 | 0.29 | Clinical |
| CHEMBL2203738 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL2203739 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL2203740 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL2203744 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL888 | 8.05 | IC50 | 9.0 | Approved |
| CHEMBL385064 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL1801774 | 7.9 | IC50 | 12.5 | Preclinical |
| CHEMBL99 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL449158 | 7.02 | IC50 | 95.95 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 34 | 56 | 5.8 |
| organism-based format | 10 | 0 | — |