S-117 · CELL-LINE · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Confirm a stable target identifier before relying on this context across project surfaces.
Confirm a stable target identifier before relying on this context across project surfaces.
S-117
Review this target as S-117.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats S-117 as ChEMBL target CHEMBL1075568. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether S-117 still has a stable protein naming contract across sources.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | S-117 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as S-117.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3545252 | 8.31 | IC50 | 4.855 | Approved |
| CHEMBL159 | 8.25 | IC50 | 5.576 | Approved |
| CHEMBL449158 | 8.23 | IC50 | 5.923 | Clinical |
| CHEMBL2363137 | 8.06 | IC50 | 8.712 | Preclinical |
| CHEMBL1972860 | 7.56 | IC50 | 27.41 | Clinical |
| CHEMBL2107358 | 7.54 | IC50 | 29.06 | Clinical |
| CHEMBL96926 | 7.39 | IC50 | 40.92 | Preclinical |
| CHEMBL1879463 | 7.12 | IC50 | 76.27 | Clinical |
| CHEMBL65 | 7.11 | IC50 | 78.15 | Preclinical |
| CHEMBL1201182 | 6.98 | IC50 | 105.3 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 98 | 5.5 |