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Target Snapshot

CHEMBL1075590 Target Snapshot

SW1710 · CELL-LINE · Homo sapiens

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106Compounds
2Assays
24Approved Drugs
97.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats SW1710 as ChEMBL target CHEMBL1075590. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
SW1710
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL1075590
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether SW1710 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSW1710
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSW1710
UniProt AccessionN/A

SW1710

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as SW1710.

Review nameSW1710
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

24
Approved
10
Phase III
10
Phase II
4
Phase I
Assay Mix

Activity Type Distribution

IC5097.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL94657 10.67 IC50 0.02135 Clinical
CHEMBL888 10.12 IC50 0.07513 Approved
CHEMBL96926 9.82 IC50 0.1495 Preclinical
CHEMBL3545252 9.33 IC50 0.466 Approved
CHEMBL252164 8.73 IC50 1.862 Clinical
CHEMBL553025 8.63 IC50 2.334 Approved
CHEMBL9470 8.54 IC50 2.91 Preclinical
CHEMBL1972860 8.29 IC50 5.164 Clinical
CHEMBL159 8.25 IC50 5.607 Approved
CHEMBL53463 7.76 IC50 17.4 Approved
Distribution

pChEMBL Value Distribution

12
5.0
17
5.5
9
6.0
6
6.5
3
7.0
2
7.5
2
8.0
3
8.5
1
9.0
1
9.5
pChEMBL
Approved Drugs

Approved Drugs

MIDOSTAURIN
CHEMBL608533
Approved 2017
Properties Compare Identifier
PONATINIB
CHEMBL1171837
Approved 2012
Properties Compare Identifier
TEMSIROLIMUS
CHEMBL1201182
Approved 2007
Properties Compare Identifier
GEMCITABINE
CHEMBL888
Approved 1996
Properties Compare Identifier
DOCETAXEL
CHEMBL3545252
Approved 1995
Properties Compare Identifier
VINORELBINE
CHEMBL553025
Approved 1994
Properties Compare Identifier
ETOPOSIDE
CHEMBL44657
Approved 1983
Properties Compare Identifier
MITOMYCIN
CHEMBL105
Approved 1981
Properties Compare Identifier
DOXORUBICIN
CHEMBL53463
Approved 1974
Properties Compare Identifier
VINBLASTINE
CHEMBL159
Approved 1965
Properties Compare Identifier
Assay Landscape

Assay Landscape

2
Total Assays
96
Tested Compounds
1
Assay Types
Functional — 2 assays, 96 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 96 6.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine