Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O75747. Use UniProt O75747 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O75747 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
Review this target as Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma, mapped to UniProt O75747. Sequence length is 1486 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma as ChEMBL target CHEMBL1163120, mapped to UniProt O75747. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O75747 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma |
| UniProt Accession | O75747 |
| Component Type | Protein |
| Sequence Length | 1486 aa |
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
Review this target as Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma, mapped to UniProt O75747. Sequence length is 1486 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3942643 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3959351 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3979343 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL230011 | 8.49 | Kd | 3.2 | Clinical |
| CHEMBL3904942 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL3889977 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL3898901 | 7.53 | IC50 | 29.3 | Preclinical |
| CHEMBL3950648 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL3907932 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL1474834 | 7.4 | Kd | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 93 | 56 | 6.3 |
| assay format | 20 | 1 | 5.2 |
| cell-based format | 8 | 2 | 6.0 |