Bromodomain-containing protein 4 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-12Protein identity stays anchored to UniProt O60885. Use UniProt O60885 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O60885 as the stable identity anchor, then attach disease evidence before program review.
Bromodomain-containing protein 4
Review this target as Bromodomain-containing protein 4, mapped to UniProt O60885. Sequence length is 1362 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bromodomain-containing protein 4 as ChEMBL target CHEMBL1163125, mapped to UniProt O60885. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Bromodomain-containing protein 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O60885 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bromodomain-containing protein 4 |
| UniProt Accession | O60885 |
| Component Type | Protein |
| Sequence Length | 1362 aa |
Bromodomain-containing protein 4
Review this target as Bromodomain-containing protein 4, mapped to UniProt O60885. Sequence length is 1362 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5170488 | 10.02 | Kd | 0.095 | Preclinical |
| CHEMBL4648912 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL5424952 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5440537 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5432745 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3895096 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL3898684 | 9.6 | Ki | 0.25 | Preclinical |
| CHEMBL5914594 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5440963 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5401253 | 9.52 | IC50 | 0.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2,063 | 817 | 6.8 |
| single protein format | 1,131 | 7,566 | 6.6 |
| assay format | 338 | 1,290 | 6.5 |
| subcellular format | 5 | 1 | 8.2 |
| organism-based format | 2 | 25 | 5.9 |
| tissue-based format | 2 | 34 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 2 | 6.9 |
| assay format | 4 | 3 | 8.4 |
| tissue-based format | 2 | 1 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 52 | 4.6 |
| assay format | 1 | 1 | 5.1 |