Microtubule-associated serine/threonine-protein kinase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9Y2H9. Use UniProt Q9Y2H9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Y2H9 as the stable identity anchor, then attach disease evidence before program review.
Microtubule-associated serine/threonine-protein kinase 1
Review this target as Microtubule-associated serine/threonine-protein kinase 1, mapped to UniProt Q9Y2H9. Sequence length is 1570 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Microtubule-associated serine/threonine-protein kinase 1 as ChEMBL target CHEMBL1163128, mapped to UniProt Q9Y2H9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Microtubule-associated serine/threonine-protein kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9Y2H9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Microtubule-associated serine/threonine-protein kinase 1 |
| UniProt Accession | Q9Y2H9 |
| Component Type | Protein |
| Sequence Length | 1570 aa |
Microtubule-associated serine/threonine-protein kinase 1
Review this target as Microtubule-associated serine/threonine-protein kinase 1, mapped to UniProt Q9Y2H9. Sequence length is 1570 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL603469 | 7.72 | Kd | 19.0 | Clinical |
| CHEMBL522892 | 7.4 | Kd | 40.0 | Clinical |
| CHEMBL388978 | 6.82 | Kd | 150.0 | Preclinical |
| CHEMBL608533 | 6.72 | Kd | 190.0 | Approved |
| CHEMBL535 | 6.7 | Kd | 200.0 | Approved |
| CHEMBL1721885 | 6.52 | Kd | 300.0 | Clinical |
| CHEMBL288441 | 6.46 | Kd | 350.0 | Approved |
| CHEMBL1789941 | 6.28 | Kd | 520.0 | Approved |
| CHEMBL4088216 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4097778 | 6.0 | IC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 47 | 15 | 6.4 |
| assay format | 16 | 0 | — |
| cell-based format | 5 | 0 | — |
| subcellular format | 5 | 0 | — |