Prolyl 4-hydroxylase subunit alpha-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P13674. Use UniProt P13674 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P13674 as the stable identity anchor, then attach disease evidence before program review.
Prolyl 4-hydroxylase subunit alpha-1
Review this target as Prolyl 4-hydroxylase subunit alpha-1, mapped to UniProt P13674. Sequence length is 534 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prolyl 4-hydroxylase subunit alpha-1 as ChEMBL target CHEMBL1250350, mapped to UniProt P13674. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Prolyl 4-hydroxylase subunit alpha-1 is the right protein anchor across sources, using UniProt P13674 as the stable mapping.
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| Preferred Name | Prolyl 4-hydroxylase subunit alpha-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P13674 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prolyl 4-hydroxylase subunit alpha-1 |
| UniProt Accession | P13674 |
| Component Type | Protein |
| Sequence Length | 534 aa |
Prolyl 4-hydroxylase subunit alpha-1
Review this target as Prolyl 4-hydroxylase subunit alpha-1, mapped to UniProt P13674. Sequence length is 534 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 9.88 | Kd | 0.132 | Preclinical |
| CHEMBL332005 | 6.85 | Ki | 140.0 | Preclinical |
| CHEMBL3586252 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL3752910 | 6.29 | Kd | 510.82 | Preclinical |
| CHEMBL332005 | 6.08 | IC50 | 840.0 | Preclinical |
| CHEMBL3586252 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL88972 | 5.58 | Ki | 2600.0 | Preclinical |
| CHEMBL88972 | 4.82 | IC50 | 15000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 3 | 6.0 |
| single protein format | 2 | 2 | 8.1 |