C-X-C chemokine receptor type 4 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P70658. Use UniProt P70658 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P70658 as the stable identity anchor, then attach disease evidence before program review.
C-X-C chemokine receptor type 4
Review this target as C-X-C chemokine receptor type 4, mapped to UniProt P70658. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats C-X-C chemokine receptor type 4 as ChEMBL target CHEMBL1250365, mapped to UniProt P70658. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether C-X-C chemokine receptor type 4 is the right protein anchor across sources, using UniProt P70658 as the stable mapping.
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| Preferred Name | C-X-C chemokine receptor type 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P70658 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | C-X-C chemokine receptor type 4 |
| UniProt Accession | P70658 |
| Component Type | Protein |
| Sequence Length | 359 aa |
C-X-C chemokine receptor type 4
Review this target as C-X-C chemokine receptor type 4, mapped to UniProt P70658. Sequence length is 359 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1242210 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL4070320 | 8.26 | IC50 | 5.47 | Preclinical |
| CHEMBL4075205 | 8.03 | IC50 | 9.24 | Preclinical |
| CHEMBL4065224 | 7.7 | IC50 | 20.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| single protein format | 1 | 3 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 8.7 |